diff --git a/backend/internal/handler/gateway_handler.go b/backend/internal/handler/gateway_handler.go
index edae3526ee..bf52f4adc0 100644
--- a/backend/internal/handler/gateway_handler.go
+++ b/backend/internal/handler/gateway_handler.go
@@ -769,8 +769,8 @@ func (h *GatewayHandler) Messages(c *gin.Context) {
 					return
 				}
 			}
-			// Bedrock CC 兼容：渠道模型映射后，清理 Anthropic API 专有字段、注入 Bedrock 必需字段
-			if err := attemptParsedReq.ReplaceBody(h.gatewayService.ApplyBedrockCCCompat(c.Request.Context(), attemptParsedReq.Body.Bytes(), attemptParsedReq.Model, account, apiKey.GroupID)); err != nil {
+			// Bedrock CC 兼容：清理 body 专有字段 + 过滤 anthropic-beta header，适用于所有转发路径
+			if err := attemptParsedReq.ReplaceBody(h.gatewayService.ApplyBedrockCCCompat(c, attemptParsedReq.Body.Bytes(), attemptParsedReq.Model, account, apiKey.GroupID)); err != nil {
 				h.errorResponse(c, http.StatusBadRequest, "invalid_request_error", "Failed to parse request body")
 				return
 			}
diff --git a/backend/internal/service/gateway_service.go b/backend/internal/service/gateway_service.go
index 20a14b53f4..eb2d547fde 100644
--- a/backend/internal/service/gateway_service.go
+++ b/backend/internal/service/gateway_service.go
@@ -5860,15 +5860,24 @@ func writeAnthropicPassthroughResponseHeaders(dst http.Header, src http.Header,
 }
 
 // ApplyBedrockCCCompat 应用 Bedrock CC 兼容转换（渠道级模型映射后调用）
-// 清理 Anthropic API 专有字段、注入 Bedrock 必需字段、修复 thinking/tool_use ID
-func (s *GatewayService) ApplyBedrockCCCompat(ctx context.Context, body []byte, model string, account *Account, groupID *int64) []byte {
-	if !s.isBedrockCCCompatEnabled(ctx, account, groupID) {
+// 清理 body 中 Anthropic API 专有字段、修复 thinking/tool_use ID、过滤 beta token，
+// 同时过滤 HTTP header 中的 anthropic-beta（防止 Passthrough 路径透传不支持的 token）。
+func (s *GatewayService) ApplyBedrockCCCompat(c *gin.Context, body []byte, model string, account *Account, groupID *int64) []byte {
+	if !s.isBedrockCCCompatEnabled(c.Request.Context(), account, groupID) {
 		return body
 	}
 	body = sanitizeBedrockCCFields(body)
 	body = sanitizeBedrockThinking(body, model)
 	body = sanitizeBedrockToolUseIDs(body)
 	body = sanitizeBedrockCCBetaTokens(body, model)
+	// 过滤 HTTP header 中的 anthropic-beta，只保留 Bedrock 支持的 token
+	if betaHeader := c.GetHeader("anthropic-beta"); betaHeader != "" {
+		if filtered := ResolveBedrockBetaTokens(betaHeader, body, model); len(filtered) > 0 {
+			c.Request.Header.Set("anthropic-beta", strings.Join(filtered, ", "))
+		} else {
+			c.Request.Header.Del("anthropic-beta")
+		}
+	}
 	return body
 }