diff --git a/UI/data/locale/en-US.ini b/UI/data/locale/en-US.ini
index 3f8238c77..28a5e2854 100644
--- a/UI/data/locale/en-US.ini
+++ b/UI/data/locale/en-US.ini
@@ -864,6 +864,7 @@ Basic.MainMenu.Help.About="&About"
 Basic.Settings.ProgramRestart="The program must be restarted for these settings to take effect."
 Basic.Settings.ConfirmTitle="Confirm Changes"
 Basic.Settings.Confirm="You have unsaved changes. Save changes?"
+Basic.Settings.MultitrackVideoDisabledSettings="%1 %2 is controlling some of your stream settings"
 
 # basic mode 'general' settings
 Basic.Settings.General="General"
diff --git a/UI/data/themes/Yami.obt b/UI/data/themes/Yami.obt
index cf9230b77..91b48ddc4 100644
--- a/UI/data/themes/Yami.obt
+++ b/UI/data/themes/Yami.obt
@@ -1376,6 +1376,11 @@ QLabel#errorLabel {
     font-weight: bold;
 }
 
+QFrame [themeID="notice"] {
+    background: var(--bg_preview);
+    border-radius: var(--border_radius);
+}
+
 /* About dialog */
 
 * [themeID="aboutName"] {
diff --git a/UI/forms/OBSBasicSettings.ui b/UI/forms/OBSBasicSettings.ui
index a144805d3..45af7e598 100644
--- a/UI/forms/OBSBasicSettings.ui
+++ b/UI/forms/OBSBasicSettings.ui
@@ -1846,6 +1846,25 @@
             <property name="bottomMargin">
              <number>0</number>
             </property>
+            <item>
+             <widget class="QFrame" name="multitrackVideoNoticeBox">
+              <property name="themeID" stdset="0">
+               <string notr="true">notice</string>
+              </property>
+              <layout class="QVBoxLayout" name="multitrackVideoNoticeBoxLayout">
+               <item>
+                <widget class="QLabel" name="multitrackVideoNotice">
+                 <property name="text">
+                  <string>Basic.Settings.MultitrackVideoDisabledSettings</string>
+                 </property>
+                 <property name="alignment">
+                  <set>Qt::AlignCenter</set>
+                 </property>
+                </widget>
+               </item>
+              </layout>
+             </widget>
+            </item>
             <item>
              <widget class="QFrame" name="widget">
               <property name="sizePolicy">
diff --git a/UI/window-basic-settings.cpp b/UI/window-basic-settings.cpp
index fc241576e..82cd64dcc 100644
--- a/UI/window-basic-settings.cpp
+++ b/UI/window-basic-settings.cpp
@@ -896,6 +896,8 @@ OBSBasicSettings::OBSBasicSettings(QWidget *parent)
 
 	obs_properties_destroy(ppts);
 
+	ui->multitrackVideoNoticeBox->setVisible(false);
+
 	InitStreamPage();
 	InitAppearancePage();
 	LoadSettings(false);
@@ -4662,6 +4664,8 @@ void OBSBasicSettings::OutputsChanged()
 		outputsChanged = true;
 		sender()->setProperty("changed", QVariant(true));
 		EnableApplyButton(true);
+
+		UpdateMultitrackVideo();
 	}
 }
 
@@ -5420,6 +5424,7 @@ void OBSBasicSettings::SimpleRecordingQualityChanged()
 	ui->simpleOutRecFormat->setVisible(!losslessQuality);
 	ui->simpleOutRecFormatLabel->setVisible(!losslessQuality);
 
+	UpdateMultitrackVideo();
 	SimpleRecordingEncoderChanged();
 	SimpleReplayBufferChanged();
 }
@@ -6343,6 +6348,114 @@ void OBSBasicSettings::UpdateMultitrackVideo()
 		toggle_available && ui->enableMultitrackVideo->isChecked() &&
 		ui->multitrackVideoConfigOverrideEnable->isChecked());
 
+	auto update_simple_output_settings = [&](bool mtv_enabled) {
+		auto recording_uses_stream_encoder =
+			ui->simpleOutRecQuality->currentData().toString() ==
+			"Stream";
+		mtv_enabled = mtv_enabled && !recording_uses_stream_encoder;
+
+		ui->simpleOutputVBitrateLabel->setDisabled(mtv_enabled);
+		ui->simpleOutputVBitrate->setDisabled(mtv_enabled);
+
+		ui->simpleOutputABitrateLabel->setDisabled(mtv_enabled);
+		ui->simpleOutputABitrate->setDisabled(mtv_enabled);
+
+		ui->simpleOutStrEncoderLabel->setDisabled(mtv_enabled);
+		ui->simpleOutStrEncoder->setDisabled(mtv_enabled);
+
+		ui->simpleOutPresetLabel->setDisabled(mtv_enabled);
+		ui->simpleOutPreset->setDisabled(mtv_enabled);
+
+		ui->simpleOutCustomLabel->setDisabled(mtv_enabled);
+		ui->simpleOutCustom->setDisabled(mtv_enabled);
+
+		ui->simpleOutStrAEncoderLabel->setDisabled(mtv_enabled);
+		ui->simpleOutStrAEncoder->setDisabled(mtv_enabled);
+	};
+
+	auto update_advanced_output_settings = [&](bool mtv_enabled) {
+		auto recording_uses_stream_video_encoder =
+			ui->advOutRecEncoder->currentText() ==
+			TEXT_USE_STREAM_ENC;
+		auto recording_uses_stream_audio_encoder =
+			ui->advOutRecAEncoder->currentData() == "none";
+		auto disable_video = mtv_enabled &&
+				     !recording_uses_stream_video_encoder;
+		auto disable_audio = mtv_enabled &&
+				     !recording_uses_stream_audio_encoder;
+
+		ui->advOutAEncLabel->setDisabled(disable_audio);
+		ui->advOutAEncoder->setDisabled(disable_audio);
+
+		ui->advOutEncLabel->setDisabled(disable_video);
+		ui->advOutEncoder->setDisabled(disable_video);
+
+		ui->advOutUseRescale->setDisabled(disable_video);
+		ui->advOutRescale->setDisabled(disable_video);
+		ui->advOutRescaleFilter->setDisabled(disable_video);
+
+		if (streamEncoderProps)
+			streamEncoderProps->SetDisabled(disable_video);
+	};
+
+	auto update_advanced_output_audio_tracks = [&](bool mtv_enabled) {
+		auto vod_track_enabled = vodTrackCheckbox &&
+					 vodTrackCheckbox->isChecked();
+
+		auto vod_track_idx_enabled = [&](size_t idx) {
+			return vod_track_enabled && vodTrack[idx] &&
+			       vodTrack[idx]->isChecked();
+		};
+
+		auto track1_warning_visible = mtv_enabled &&
+					      (ui->advOutTrack1->isChecked() ||
+					       vod_track_idx_enabled(1));
+		auto track1_disabled = track1_warning_visible &&
+				       !ui->advOutRecTrack1->isChecked();
+		ui->advOutTrack1BitrateLabel->setDisabled(track1_disabled);
+		ui->advOutTrack1Bitrate->setDisabled(track1_disabled);
+
+		auto track2_warning_visible = mtv_enabled &&
+					      (ui->advOutTrack2->isChecked() ||
+					       vod_track_idx_enabled(2));
+		auto track2_disabled = track2_warning_visible &&
+				       !ui->advOutRecTrack2->isChecked();
+		ui->advOutTrack2BitrateLabel->setDisabled(track2_disabled);
+		ui->advOutTrack2Bitrate->setDisabled(track2_disabled);
+
+		auto track3_warning_visible = mtv_enabled &&
+					      (ui->advOutTrack3->isChecked() ||
+					       vod_track_idx_enabled(3));
+		auto track3_disabled = track3_warning_visible &&
+				       !ui->advOutRecTrack3->isChecked();
+		ui->advOutTrack3BitrateLabel->setDisabled(track3_disabled);
+		ui->advOutTrack3Bitrate->setDisabled(track3_disabled);
+
+		auto track4_warning_visible = mtv_enabled &&
+					      (ui->advOutTrack4->isChecked() ||
+					       vod_track_idx_enabled(4));
+		auto track4_disabled = track4_warning_visible &&
+				       !ui->advOutRecTrack4->isChecked();
+		ui->advOutTrack4BitrateLabel->setDisabled(track4_disabled);
+		ui->advOutTrack4Bitrate->setDisabled(track4_disabled);
+
+		auto track5_warning_visible = mtv_enabled &&
+					      (ui->advOutTrack5->isChecked() ||
+					       vod_track_idx_enabled(5));
+		auto track5_disabled = track5_warning_visible &&
+				       !ui->advOutRecTrack5->isChecked();
+		ui->advOutTrack5BitrateLabel->setDisabled(track5_disabled);
+		ui->advOutTrack5Bitrate->setDisabled(track5_disabled);
+
+		auto track6_warning_visible = mtv_enabled &&
+					      (ui->advOutTrack6->isChecked() ||
+					       vod_track_idx_enabled(6));
+		auto track6_disabled = track6_warning_visible &&
+				       !ui->advOutRecTrack6->isChecked();
+		ui->advOutTrack6BitrateLabel->setDisabled(track6_disabled);
+		ui->advOutTrack6Bitrate->setDisabled(track6_disabled);
+	};
+
 	if (available) {
 		OBSDataAutoRelease settings;
 		{
@@ -6384,6 +6497,26 @@ void OBSBasicSettings::UpdateMultitrackVideo()
 					.arg(multitrack_video_name,
 					     ui->service->currentText()));
 		}
+
+		auto disabled_text =
+			QTStr("Basic.Settings.MultitrackVideoDisabledSettings")
+				.arg(ui->service->currentText())
+				.arg(multitrack_video_name);
+
+		ui->multitrackVideoNotice->setText(disabled_text);
+
+		auto mtv_enabled = ui->enableMultitrackVideo->isChecked();
+		ui->multitrackVideoNoticeBox->setVisible(mtv_enabled);
+
+		update_simple_output_settings(mtv_enabled);
+		update_advanced_output_settings(mtv_enabled);
+		update_advanced_output_audio_tracks(mtv_enabled);
+	} else {
+		ui->multitrackVideoNoticeBox->setVisible(false);
+
+		update_simple_output_settings(false);
+		update_advanced_output_settings(false);
+		update_advanced_output_audio_tracks(false);
 	}
 }