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These changes should only affect output when an input block has a species appearing more than once, with the exception being the MAF to multiple FASTA blocks converters: the FASTA headers have been revised to included the sequence index for a species in a block as well as the block index. A new tool "Split MAF Blocks by Species" has been added that will split MAF blocks into the complete combination of multiple blocks when a species appears more than once.
45 lines
1.4 KiB
Python
45 lines
1.4 KiB
Python
#!/usr/bin/env python
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"""
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Read a maf and split blocks by unique species combinations
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"""
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import sys
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from galaxy import eggs
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import pkg_resources; pkg_resources.require( "bx-python" )
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from bx.align import maf
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from galaxy.tools.util import maf_utilities
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from galaxy.util import string_as_bool
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assert sys.version_info[:2] >= ( 2, 4 )
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def __main__():
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try:
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maf_reader = maf.Reader( open( sys.argv[1] ) )
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except Exception, e:
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maf_utilities.tool_fail( "Error opening MAF: %s" % e )
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try:
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out = maf.Writer( open( sys.argv[2], "w") )
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except Exception, e:
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maf_utilities.tool_fail( "Error opening file for output: %s" % e )
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try:
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collapse_columns = string_as_bool( sys.argv[3] )
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except Exception, e:
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maf_utilities.tool_fail( "Error determining collapse columns value: %s" % e )
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start_count = 0
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end_count = 0
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for start_count, start_block in enumerate( maf_reader ):
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for block in maf_utilities.iter_blocks_split_by_species( start_block ):
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if collapse_columns:
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block.remove_all_gap_columns()
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out.write( block )
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end_count += 1
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out.close()
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if end_count:
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print "%i alignment blocks created from %i original blocks." % ( end_count, start_count + 1 )
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else:
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print "No alignment blocks were created."
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if __name__ == "__main__": __main__()
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