diff --git a/test/integration/objectstore/test_remote_objectstore_cache_operations.py b/test/integration/objectstore/test_remote_objectstore_cache_operations.py
index 8e7d396c398..e6d114234de 100644
--- a/test/integration/objectstore/test_remote_objectstore_cache_operations.py
+++ b/test/integration/objectstore/test_remote_objectstore_cache_operations.py
@@ -20,6 +20,13 @@ class CacheOperationTestCase(BaseSwiftObjectStoreIntegrationTestCase):
         hda = self.dataset_populator.new_dataset(history_id, content="123", wait=True)
         return hda
 
+    def upload_bam_dataset(self):
+        history_id = self.dataset_populator.new_history()
+        hda = self.dataset_populator.new_dataset(
+            history_id, content=open(self.test_data_resolver.get_filename("1.bam"), "rb"), file_type="bam", wait=True
+        )
+        return hda
+
     def test_cache_populated(self):
         self.upload_dataset()
         assert files_count(self.object_store_cache_path) == 1
@@ -34,6 +41,23 @@ class CacheOperationTestCase(BaseSwiftObjectStoreIntegrationTestCase):
         assert content == "123\n"
         assert files_count(self.object_store_cache_path) == 1
 
+    def test_cache_repopulated_metadata_file(self):
+        hda = self.upload_bam_dataset()
+        assert files_count(self.object_store_cache_path) == 2
+        response = self._get(
+            f'histories/{hda["history_id"]}/contents/{hda["id"]}/metadata_file?metadata_name=bam_index'
+        )
+        assert len(response.content) > 0
+        response.raise_for_status()
+        shutil.rmtree(self.object_store_cache_path)
+        assert files_count(self.object_store_cache_path) == 0
+        response = self._get(
+            f'histories/{hda["history_id"]}/contents/{hda["id"]}/metadata_file?metadata_name=bam_index'
+        )
+        response.raise_for_status()
+        assert files_count(self.object_store_cache_path) == 1
+        assert len(response.content) > 0
+
     def test_delete_item_not_in_cache(self):
         hda = self.upload_dataset()
         assert files_count(self.object_store_cache_path) == 1