diff --git a/packages/config/galaxy/project_galaxy_config.py b/packages/config/galaxy/project_galaxy_config.py
deleted file mode 100644
index 77995dd1d2f..00000000000
--- a/packages/config/galaxy/project_galaxy_config.py
+++ /dev/null
@@ -1,7 +0,0 @@
-__version__ = "22.1.0"
-
-PROJECT_NAME = "galaxy-config"
-PROJECT_URL = "https://github.com/galaxyproject/galaxy"
-PROJECT_AUTHOR = "Galaxy Project and Community"
-PROJECT_DESCRIPTION = "Galaxy Configuration"
-PROJECT_EMAIL = "galaxy-committers@lists.galaxyproject.org"
diff --git a/packages/config/pyproject.toml b/packages/config/pyproject.toml
new file mode 120000
index 00000000000..01a3b08b887
--- /dev/null
+++ b/packages/config/pyproject.toml
@@ -0,0 +1 @@
+../package-pyproject.toml
\ No newline at end of file
diff --git a/packages/config/requirements.txt b/packages/config/requirements.txt
deleted file mode 100644
index b0cce9c6075..00000000000
--- a/packages/config/requirements.txt
+++ /dev/null
@@ -1,4 +0,0 @@
-boltons
-pykwalify
-PyYAML
-requests
diff --git a/packages/config/setup.cfg b/packages/config/setup.cfg
new file mode 100644
index 00000000000..fcae838acdf
--- /dev/null
+++ b/packages/config/setup.cfg
@@ -0,0 +1,47 @@
+[metadata]
+author = Galaxy Project and Community
+author_email = galaxy-committers@lists.galaxyproject.org
+classifiers =
+    Development Status :: 5 - Production/Stable
+    Environment :: Console
+    Intended Audience :: Developers
+    License :: OSI Approved :: Academic Free License (AFL)
+    Natural Language :: English
+    Operating System :: POSIX
+    Programming Language :: Python :: 3
+    Programming Language :: Python :: 3.7
+    Programming Language :: Python :: 3.8
+    Programming Language :: Python :: 3.9
+    Programming Language :: Python :: 3.10
+    Topic :: Software Development
+    Topic :: Software Development :: Code Generators
+    Topic :: Software Development :: Testing
+description = Galaxy configuration
+keywords =
+    Galaxy
+license = AFL
+license_files =
+    LICENSE
+long_description = file: README.rst, HISTORY.rst
+long_description_content_type = text/x-rst
+name = galaxy-config
+url = https://github.com/galaxyproject/galaxy
+version = 22.5.0.dev0
+
+[options]
+include_package_data = True
+install_requires =
+    galaxy-util
+    boltons
+    pykwalify
+    PyYAML
+packages = find:
+python_requires = >=3.7
+
+[options.entry_points]
+console_scripts =
+        galaxy-config = galaxy.config.script:main
+
+[options.packages.find]
+exclude =
+    tests*
diff --git a/packages/config/setup.py b/packages/config/setup.py
deleted file mode 100644
index 1a808b04f59..00000000000
--- a/packages/config/setup.py
+++ /dev/null
@@ -1,92 +0,0 @@
-#!/usr/bin/env python
-
-import ast
-import os
-import re
-
-from setuptools import (
-    find_packages,
-    setup,
-)
-
-SOURCE_DIR = "galaxy"
-
-project_short_name = os.path.basename(os.path.dirname(os.path.realpath(__file__)))
-with open(f"{SOURCE_DIR}/project_galaxy_{project_short_name}.py") as f:
-    init_contents = f.read()
-
-
-def get_var(var_name):
-    pattern = re.compile(rf"{var_name}\s+=\s+(.*)")
-    match = pattern.search(init_contents)
-    assert match
-    return str(ast.literal_eval(match.group(1)))
-
-
-version = get_var("__version__")
-PROJECT_NAME = get_var("PROJECT_NAME")
-PROJECT_URL = get_var("PROJECT_URL")
-PROJECT_AUTHOR = get_var("PROJECT_AUTHOR")
-PROJECT_EMAIL = get_var("PROJECT_EMAIL")
-PROJECT_DESCRIPTION = get_var("PROJECT_DESCRIPTION")
-
-PACKAGES = find_packages(where=".", exclude=["tests*"])
-ENTRY_POINTS = """
-        [console_scripts]
-        galaxy-config=galaxy.config.script:main
-"""
-PACKAGE_DATA = {
-    # Be sure to update MANIFEST.in for source dist.
-    "galaxy": [
-        "config/schemas/*.yml",
-        "config/sample/*",
-    ],
-}
-PACKAGE_DIR = {
-    SOURCE_DIR: SOURCE_DIR,
-}
-
-readme = open("README.rst").read()
-history = open("HISTORY.rst").read()
-
-if os.path.exists("requirements.txt"):
-    requirements = open("requirements.txt").read().split("\n")
-else:
-    # In tox, it will cover them anyway.
-    requirements = []
-
-setup(
-    name=PROJECT_NAME,
-    version=version,
-    description=PROJECT_DESCRIPTION,
-    long_description=readme + "\n\n" + history,
-    long_description_content_type="text/x-rst",
-    author=PROJECT_AUTHOR,
-    author_email=PROJECT_EMAIL,
-    url=PROJECT_URL,
-    packages=PACKAGES,
-    entry_points=ENTRY_POINTS,
-    package_data=PACKAGE_DATA,
-    package_dir=PACKAGE_DIR,
-    include_package_data=True,
-    install_requires=requirements,
-    license="AFL",
-    zip_safe=False,
-    keywords="galaxy",
-    classifiers=[
-        "Development Status :: 5 - Production/Stable",
-        "Intended Audience :: Developers",
-        "Environment :: Console",
-        "License :: OSI Approved :: Academic Free License (AFL)",
-        "Operating System :: POSIX",
-        "Topic :: Software Development",
-        "Topic :: Software Development :: Code Generators",
-        "Topic :: Software Development :: Testing",
-        "Natural Language :: English",
-        "Programming Language :: Python :: 3",
-        "Programming Language :: Python :: 3.7",
-        "Programming Language :: Python :: 3.8",
-        "Programming Language :: Python :: 3.9",
-        "Programming Language :: Python :: 3.10",
-    ],
-)