diff --git a/lib/galaxy/dependencies/dev-requirements.txt b/lib/galaxy/dependencies/dev-requirements.txt
index d28bada04ad..2de873dbd20 100644
--- a/lib/galaxy/dependencies/dev-requirements.txt
+++ b/lib/galaxy/dependencies/dev-requirements.txt
@@ -227,7 +227,7 @@ tqdm==4.64.0; python_version >= "2.7" and python_full_version < "3.0.0" or pytho
 trio-websocket==0.9.2; python_version >= "3.7" and python_version < "4.0"
 trio==0.21.0; python_version >= "3.7" and python_version < "4.0"
 tuspy==0.2.5
-tuswsgi==0.5.4
+tuswsgi==0.5.5
 twill==3.0.2
 typed-ast==1.5.4; python_version < "3.8" and implementation_name == "cpython" and python_full_version >= "3.6.2" and python_version >= "3.7"
 typing-extensions==4.2.0; python_version >= "3.7"
diff --git a/lib/galaxy/dependencies/pinned-requirements.txt b/lib/galaxy/dependencies/pinned-requirements.txt
index 74f8f510fc7..9e4d35bb5bd 100644
--- a/lib/galaxy/dependencies/pinned-requirements.txt
+++ b/lib/galaxy/dependencies/pinned-requirements.txt
@@ -159,7 +159,7 @@ tenacity==8.0.1; python_version >= "3.6"
 tifffile==2021.11.2; python_version >= "3.7"
 tornado==6.1; python_version >= "3.5"
 tqdm==4.64.0; python_version >= "2.7" and python_full_version < "3.0.0" or python_full_version >= "3.4.0"
-tuswsgi==0.5.4
+tuswsgi==0.5.5
 typing-extensions==4.2.0; python_version >= "3.7"
 tzlocal==2.1; python_version >= "2.7" and python_full_version < "3.0.0" or python_full_version >= "3.5.0" and python_version < "4"
 ubiquerg==0.6.2