diff --git a/lib/galaxy/dependencies/dev-requirements.txt b/lib/galaxy/dependencies/dev-requirements.txt
index 1c55ef40157..dd0b7d17ee4 100644
--- a/lib/galaxy/dependencies/dev-requirements.txt
+++ b/lib/galaxy/dependencies/dev-requirements.txt
@@ -224,7 +224,7 @@ sphinxcontrib-jsmath==1.0.1; python_version >= "3.5"
 sphinxcontrib-qthelp==1.0.3; python_version >= "3.5"
 sphinxcontrib-serializinghtml==1.1.4; python_version >= "3.5"
 sqlalchemy-migrate==0.13.0
-sqlalchemy==1.4.15
+sqlalchemy==1.4.17
 sqlitedict==1.7.0
 sqlparse==0.4.1; python_version >= "3.5"
 starlette-context==0.3.2; python_version >= "3.7"
diff --git a/lib/galaxy/dependencies/pinned-requirements.txt b/lib/galaxy/dependencies/pinned-requirements.txt
index 0fc5412b01b..01a565e08c0 100644
--- a/lib/galaxy/dependencies/pinned-requirements.txt
+++ b/lib/galaxy/dependencies/pinned-requirements.txt
@@ -180,7 +180,7 @@ six==1.15.0; python_version >= "3.6" and python_full_version < "3.0.0" and pytho
 social-auth-core==3.3.0
 sortedcontainers==2.3.0
 sqlalchemy-migrate==0.13.0
-sqlalchemy==1.4.15
+sqlalchemy==1.4.17
 sqlitedict==1.7.0
 sqlparse==0.4.1; python_version >= "3.5"
 starlette-context==0.3.2; python_version >= "3.7"
diff --git a/packages/data/requirements.txt b/packages/data/requirements.txt
index dffb7fb73d5..68d15e0e127 100644
--- a/packages/data/requirements.txt
+++ b/packages/data/requirements.txt
@@ -13,7 +13,7 @@ pycryptodome
 pydantic
 pysam
 social-auth-core[openidconnect]==3.3.0
-SQLAlchemy>=1.4.15,<2
+SQLAlchemy>=1.4.17,<2
 sqlalchemy-migrate
 tifffile<=2021.2.26 # Last release compatible with python 3.6
 WebOb
diff --git a/packages/web_framework/requirements.txt b/packages/web_framework/requirements.txt
index 0529d917047..1a823e07817 100644
--- a/packages/web_framework/requirements.txt
+++ b/packages/web_framework/requirements.txt
@@ -8,5 +8,5 @@ pydantic<1.8
 requests
 Routes
 six
-SQLAlchemy>=1.4.15,<2
+SQLAlchemy>=1.4.17,<2
 WebOb
diff --git a/packages/web_stack/requirements.txt b/packages/web_stack/requirements.txt
index 6209652082a..724f406ef4c 100644
--- a/packages/web_stack/requirements.txt
+++ b/packages/web_stack/requirements.txt
@@ -1,2 +1,2 @@
-SQLAlchemy>=1.4.15,<2
+SQLAlchemy>=1.4.17,<2
 galaxy-util
diff --git a/pyproject.toml b/pyproject.toml
index 153ed5bc170..ce8e19ef30e 100644
--- a/pyproject.toml
+++ b/pyproject.toml
@@ -69,7 +69,7 @@ requests = "*"
 Routes = "*"
 social-auth-core = {version = "==3.3.0", extras = ["openidconnect"]}
 sortedcontainers = "*"
-SQLAlchemy = ">=1.4.15,<2"
+SQLAlchemy = ">=1.4.17,<2"
 sqlalchemy-migrate = "*"
 sqlitedict = "*"
 sqlparse = "*"