diff --git a/lib/galaxy/__init__.py b/lib/galaxy/__init__.py
index 6ba73189149..f54b209016e 100644
--- a/lib/galaxy/__init__.py
+++ b/lib/galaxy/__init__.py
@@ -12,8 +12,9 @@ Galaxy root package -- this is a namespace package.
 import os, sys
 from distutils.sysconfig import get_config_vars
 
-if ( os.uname()[-1] in ( 'i386', 'ppc' ) and sys.platform == 'darwin' and os.path.abspath( sys.prefix ).startswith( '/System' ) ) or \
-   ( sys.platform == 'darwin' and get_config_vars().get('UNIVERSALSDK', '').strip() ):
+if sys.version_info[:2] == ( 2, 5 ) and \
+        ( ( os.uname()[-1] in ( 'i386', 'ppc' ) and sys.platform == 'darwin' and os.path.abspath( sys.prefix ).startswith( '/System' ) ) or \
+          ( sys.platform == 'darwin' and get_config_vars().get('UNIVERSALSDK', '').strip() ) ):
     # Has to be before anything imports pkg_resources
     def _get_platform_monkeypatch():
         plat = distutils.util._get_platform()