diff --git a/config/galaxy.yml.interactivetools b/config/galaxy.yml.interactivetools
index 570b14415ac..fe2d5892086 100644
--- a/config/galaxy.yml.interactivetools
+++ b/config/galaxy.yml.interactivetools
@@ -32,7 +32,9 @@ galaxy:
   interactivetools_map: database/interactivetools_map.sqlite
   # If you develop InteractiveTools locally and do not have a full FQDN you can
   # use an arbritrary one, e.g. 'my-hostname' here, if you set this hostname in your
-  # job_conf.xml as well (see the corresponding comment).
+  # job_conf.xml as well (see the corresponding comment). If running mac OS X, do not match the
+  # "http://host.docker.internal:8080" used at galaxy_infrastructure_url in the galaxy.yml file, 
+  # and use an arbitrary name here instead.
   # Please make sure that in the local development case you use https://localhost:8080 to access
   # your Galaxy. http://my-hostname:8080 will not work.
   # galaxy_infrastructure_url: http://my-hostname:8080