diff --git a/packages/app/setup.cfg b/packages/app/setup.cfg
index 87c5e1ffbeb..e56f8f0c182 100644
--- a/packages/app/setup.cfg
+++ b/packages/app/setup.cfg
@@ -49,7 +49,7 @@ install_requires =
     pebble
     pulsar-galaxy-lib>=0.15.0.dev0
     pydantic>=2.7.4
-    pydantic-ai>=0.1.16
+    pydantic-ai>=1.99.0
     pysam>=0.21
     python-slugify
     PyJWT