diff --git a/lib/galaxy/config/sample/datatypes_conf.xml.sample b/lib/galaxy/config/sample/datatypes_conf.xml.sample
index c9eb1816b46..bba6a99cf27 100644
--- a/lib/galaxy/config/sample/datatypes_conf.xml.sample
+++ b/lib/galaxy/config/sample/datatypes_conf.xml.sample
@@ -637,6 +637,7 @@
     <datatype extension="gal" type="galaxy.datatypes.microarrays:Gal" display_in_upload="true"/>
     <datatype extension="rdata" type="galaxy.datatypes.binary:RData" mimetype="application/x-gzip" display_in_upload="true" description="Stored data from an R session"/>
     <datatype extension="rdata.sce" type="galaxy.datatypes.binary:RData" mimetype="application/x-gzip" subclass="true" display_in_upload="true" description="Stored RDS from a SingleCellObject"/>
+    <datatype extension="rdata.eset" type="galaxy.datatypes.binary:RData" mimetype="application/x-gzip" subclass="true" display_in_upload="true" description="Stored RDS from a ExpressionSet Object"/>
     <datatype extension="rdata.xcms.raw" type="galaxy.datatypes.binary:RData" mimetype="application/x-gzip" subclass="true" display_in_upload="true"/>
     <datatype extension="rdata.msnbase.raw" type="galaxy.datatypes.binary:RData" mimetype="application/x-gzip" subclass="true" display_in_upload="true"/>
     <datatype extension="rdata.xcms.findchrompeaks" type="galaxy.datatypes.binary:RData" mimetype="application/x-gzip" subclass="true" display_in_upload="true"/>