diff --git a/lib/galaxy/dependencies/pinned-requirements.txt b/lib/galaxy/dependencies/pinned-requirements.txt
index c895b2f481c..a4f16df0efd 100644
--- a/lib/galaxy/dependencies/pinned-requirements.txt
+++ b/lib/galaxy/dependencies/pinned-requirements.txt
@@ -27,7 +27,7 @@ Beaker==1.7.0
 dictobj==0.3.1
 nose==1.3.7
 Parsley==1.3
-six==1.9.0
+six==1.10.0
 Whoosh==2.7.4
 testfixtures==4.10.0