diff --git a/lib/galaxy/dependencies/dev-requirements.txt b/lib/galaxy/dependencies/dev-requirements.txt
index d19c491dae0..8c8ac28315f 100644
--- a/lib/galaxy/dependencies/dev-requirements.txt
+++ b/lib/galaxy/dependencies/dev-requirements.txt
@@ -87,7 +87,7 @@ junit-xml==1.9
 keyring==25.7.0 ; platform_machine != 'ppc64le' and platform_machine != 's390x'
 kiwisolver==1.5.0
 librt==0.9.0 ; platform_python_implementation != 'PyPy'
-lxml==6.0.4
+lxml==6.1.0
 markdown-it-py==3.0.0 ; python_full_version < '3.11'
 markdown-it-py==4.0.0 ; python_full_version >= '3.11'
 markdown-it-reporter==0.0.2
diff --git a/lib/galaxy/dependencies/pinned-requirements.txt b/lib/galaxy/dependencies/pinned-requirements.txt
index e3fcaa22cb0..63806d4cb13 100644
--- a/lib/galaxy/dependencies/pinned-requirements.txt
+++ b/lib/galaxy/dependencies/pinned-requirements.txt
@@ -139,7 +139,7 @@ legacy-cgi==2.6.4 ; python_full_version >= '3.13'
 limits==5.8.0
 logfire==4.32.1
 logfire-api==4.32.1
-lxml==6.0.4
+lxml==6.1.0
 mako==1.3.11
 markdown==3.10.2
 markdown-it-py==3.0.0 ; python_full_version < '3.11'
diff --git a/lib/galaxy/dependencies/pinned-test-requirements.txt b/lib/galaxy/dependencies/pinned-test-requirements.txt
index 8a4ddf9b2d2..d5d92573d1c 100644
--- a/lib/galaxy/dependencies/pinned-test-requirements.txt
+++ b/lib/galaxy/dependencies/pinned-test-requirements.txt
@@ -68,7 +68,7 @@ jsonschema-specifications==2025.9.1
 junit-xml==1.9
 kiwisolver==1.5.0
 librt==0.9.0 ; platform_python_implementation != 'PyPy'
-lxml==6.0.4
+lxml==6.1.0
 markdown-it-py==3.0.0 ; python_full_version < '3.11'
 markdown-it-py==4.0.0 ; python_full_version >= '3.11'
 markupsafe==3.0.3